MS4A2 (Human) Recombinant Protein (Q01)
产品名称: MS4A2 (Human) Recombinant Protein (Q01)
英文名称: MS4A2 (Human) Recombinant Protein (Q01)
产品编号: H00002206-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human MS4A2 partial ORF ( NP_000130, 1 a.a. - 59 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQE
- Theoretical MW (kDa):
- 32.23
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 2206
- GeneBank Accession#:
- NM_000139
- Protein Accession#:
- NP_000130
- Gene Name:
- MS4A2
- Gene Alias:
- APY,ATOPY,FCER1B,FCERI,IGEL,IGER,IGHER,MS4A1
- Gene Description:
- membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of family members. Alternative splicing results in multiple transcript variants encoding different isoforms
- Other Designations:
- Fc IgE receptor, beta chain,Fc epsilon receptor I beta-chain,Fc-epsilon receptor I beta-chain,High affinity immunoglobulin epsilon receptor beta-subunit (FcERI) (IgE Fc receptor, beta-subunit) (Fc epsilon receptor I beta-chain),IgE responsiveness (atopic)
- Gene Pathway
- Related Disease
- Angioneurotic Edema
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Brain Ischemia
- Bronchial Hyperreactivity
- Bronchiolitis, Viral
- Calcinosis
- Cardiovascular Diseases
- Cerebrovascular Disorders
- Chlamydia Infections
- Chronic Disease
- Constriction, Pathologic
- Coronary Artery Disease
- Coronary Disease
- Dermatitis, Atopic
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2