TGM2 polyclonal antibody
产品名称： TGM2 polyclonal antibody
英文名称： TGM2 polyclonal antibody
产品编号： PAB7291
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of TGM2.
- Immunogen:
- A synthetic peptide corresponding to human TGM2.
- Sequence:
- C-NFESDKLKAVKGFR
- Host:
- Goat
- Theoretical MW (kDa):
- 77.3
- Reactivity:
- Human
- Specificity:
- This antibody is expected to recognize isoform a (NP_004604.2) only.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:128000)
Western Blot (0.03-0.1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis.
Verma A, Wang H, Manavathi B, Fok JY, Mann AP, Kumar R, Mehta K.Cancer Res. 2006 Nov 1;66(21):10525-33.
- Entrez GeneID:
- 7052
- Protein Accession#:
- NP_004604.2
- Gene Name:
- TGM2
- Gene Alias:
- G-ALPHA-h,GNAH,TG2,TGC
- Gene Description:
- transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
- Omim ID:
- 190196
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- C polypeptide,OTTHUMP00000030960,TGase C,TGase-H,protein-glutamine-gamma-glutamyltransferase,tissue transglutaminase,transglutaminase 2,transglutaminase C
- Gene Pathway