TMC6 polyclonal antibody
产品名称： TMC6 polyclonal antibody
英文名称： TMC6 polyclonal antibody
产品编号： PAB13360
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of TMC6.
- Immunogen:
- A synthetic peptide corresponding to internal region 15 amino acids of human TMC6.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses.
Lazarczyk M, Pons C, Mendoza JA, Cassonnet P, Jacob Y, Favre M.J Exp Med. 2008 Jan 21;205(1):35-42. Epub 2007 Dec 24.
- 2.
- TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins.
Keresztes G, Mutai H, Heller S.BMC Genomics. 2003 Jun 17;4(1):24. Epub 2003 Jun 17.
- 3.
- Epidermodysplasia verruciformis. Immunological and nonimmunological surveillance mechanisms: role in tumor progression.
Majewski S, Jablonska S, Orth G.Clin Dermatol. 1997 May-Jun;15(3):321-34.
- Entrez GeneID:
- 11322
- Protein Accession#:
- AAM44452
- Gene Name:
- TMC6
- Gene Alias:
- EV1,EVER1,EVIN1,FLJ17776,LAK-4P
- Gene Description:
- transmembrane channel-like 6
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs. [provided by RefSeq
- Other Designations:
- epidermodysplasia verruciformis 1,expressed in activated T/LAK lymphocytes