IKK-alpha/beta (phospho S176) polyclonal antibody
产品名称： IKK-alpha/beta (phospho S176) polyclonal antibody
英文名称： IKK-alpha/beta (phospho S176) polyclonal antibody
产品编号： PAB16976
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of IKK-alpha/beta.
- Immunogen:
- Synthetic phosphopeptide corresponding to residues surrounding S176 of human IKK-alpha/beta.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody detects endogenous levels of IKK-alpha/IKK-beta only when phosphorylated at serine 180/181.
- Form:
- Liquid
- Storage Buffer:
- In 20 mM PBS, 0.15 M NaCl, pH 7.2 (0.01% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
ELISA (1:4000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Proteasome inhibitors induce death but activate NF-kappaB on endometrial carcinoma cell lines and primary culture explants.
Dolcet X, Llobet D, Encinas M, Pallares J, Cabero A, Schoenenberger JA, Comella JX, Matias-Guiu X.J Biol Chem. 2006 Aug 4;281(31):22118-30. Epub 2006 May 30.
- 2.
- NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176.
Ling L, Cao Z, Goeddel DV.Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3792-7.
- 3.
- IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation.
Mercurio F, Zhu H, Murray BW, Shevchenko A, Bennett BL, Li J, Young DB, Barbosa M, Mann M, Manning A, Rao A.Science. 1997 Oct 31;278(5339):860-6.
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- ELISA