SCN11A monoclonal antibody (M02), clone 2B10
产品名称: SCN11A monoclonal antibody (M02), clone 2B10
英文名称: SCN11A monoclonal antibody (M02), clone 2B10
产品编号: H00011280-M02
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant SCN11A.
- Immunogen:
- SCN11A (NP_054858, 1726 a.a. ~ 1791 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- TTTKRKEEERGAAIIQKAFRKYMMKVTKGDQGDQNDLENGPHSPLQTLCNGDLSSFGVAKGKVHCD
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33 KDa) .
- MSDS:
- Download
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 11280
- GeneBank Accession#:
- NM_014139
- Protein Accession#:
- NP_054858
- Gene Name:
- SCN11A
- Gene Alias:
- NAV1.9,NaN,SCN12A,SNS-2
- Gene Description:
- sodium channel, voltage-gated, type XI, alpha subunit
- Omim ID:
- 604385
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.[supplied by OMIM
- Other Designations:
- sodium channel, voltage-gated, type XI, alpha,sodium channel, voltage-gated, type XI, alpha polypeptide,sodium channel, voltage-gated, type XII, alpha polypeptide,voltage-gated sodium channel Nav1.9