ABCC2 polyclonal antibody (A01)
产品名称： ABCC2 polyclonal antibody (A01)
英文名称： ABCC2 polyclonal antibody (A01)
产品编号： H00001244-A01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant ABCC2.
- Immunogen:
- ABCC2 (NP_000383, 214 a.a. ~ 313 a.a) partial recombinant protein with GST tag.
- Sequence:
- LKGYKRPLTLEDVWEVDEEMKTKTLVSKFETHMKRELQKARRALQRRQEKSSQQNSGARLPGLNKNQSQSQDALVLEDVEKKKKKSGTKKDVPKSWLMKA
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
Download
- Application Image
- ELISA
- Entrez GeneID:
- 1244
- GeneBank Accession#:
- NM_000392
- Protein Accession#:
- NP_000383
- Gene Name:
- ABCC2
- Gene Alias:
- ABC30,CMOAT,DJS,KIAA1010,MRP2,cMRP
- Gene Description:
- ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq
- Other Designations:
- OTTHUMP00000020267,canalicular multispecific organic anion transporter
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Alzheimer Disease
- Arthritis, Rheumatoid
- Bile Duct Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Ductal, Breast
- Carcinoma, Endometrioid
- Carcinoma, Non-Small-Cell Lung
- Cholangiocarcinoma
- Cholestasis, Intrahepatic
- Colon cancer
- Colonic Neoplasms
- Colorectal Neoplasms
- Cystadenocarcinoma, Serous
- Diarrhea
- Disease Progression
- Drug Toxicity