FGF2 (Human) Recombinant Protein
产品名称: FGF2 (Human) Recombinant Protein
英文名称: FGF2 (Human) Recombinant Protein
产品编号: P3469
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human FGF2 (NP_001997.5, 143 a.a. - 288 a.a.) partial recombinant protein expressed in Escherichia coli.
- Sequence:
- MPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
- Theoretical MW (kDa):
- 16.5
- Form:
- Liquid
- Preparation Method:
- Escherichia coli expression system
- Purification:
- Conventional Chromatography
- Concentration:
- 1 mg/mL
- Purity:
- > 95% by SDS-PAGE
- Endotoxin Level:
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Activity:
- Measured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast. The ED50 for this effect is 0.1-1.5 ng/mL.
- Storage Buffer:
- In 50 mM Tris, pH 8.0
- Storage Instruction:
- Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 3 ug protein in 15% SDS-PAGE
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 2247
- Protein Accession#:
- NP_001997.5
- Gene Name:
- FGF2
- Gene Alias:
- BFGF,FGFB,HBGF-2
- Gene Description:
- fibroblast growth factor 2 (basic)
- Omim ID:
- 134920
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq
- Other Designations:
- basic fibroblast growth factor bFGF,fibroblast growth factor 2,heparin-binding growth factor 2,prostatropin
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Arthritis, Psoriatic
- Birth Weight
- Cardiovascular Diseases
- Chorioamnionitis
- Cleft Lip
- Cleft Palate
- Depressive Disorder, Major
- Diabetes Complications
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetic Retinopathy
- Edema
- Fetal Membranes, Premature Rupture
- Gastrointestinal Diseases
- Genetic Predisposition to Disease
- Glioblastoma
- Glioma