EIF2S1 polyclonal antibody
产品名称： EIF2S1 polyclonal antibody
英文名称： EIF2S1 polyclonal antibody
产品编号： PAB16981
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of EIF2S1.
- Immunogen:
- A synthetic peptide corresponding to residues surrounding S49 of human EIF2S1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody detects endogenous levels of total EIF2S1 protein.
- Form:
- Liquid
- Storage Buffer:
- In 20 mM PBS, 0.15 M NaCl, pH 7.2 (0.01% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Regulation of translation initiation following stress.
Sheikh MS, Fornace AJ Jr.Oncogene. 1999 Nov 1;18(45):6121-8.
- 2.
- Involvement of double-stranded RNA-activated protein kinase in the synergistic activation of nuclear factor-kappaB by tumor necrosis factor-alpha and gamma-interferon in preneuronal cells.
Cheshire JL, Williams BR, Baldwin AS Jr.J Biol Chem. 1999 Feb 19;274(8):4801-6.
- 3.
- Eukaryotic initiation factor eIF2.
Kimball SR.Int J Biochem Cell Biol. 1999 Jan;31(1):25-9.
- Entrez GeneID:
- 1965
- Protein Accession#:
- P05198
- Gene Name:
- EIF2S1
- Gene Alias:
- EIF-2,EIF-2A,EIF-2alpha,EIF2,EIF2A
- Gene Description:
- eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
- Omim ID:
- 603907
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD, MIM 603908), and gamma (52 kD, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM
- Other Designations:
- eIF-2-alpha,eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD )
- Related Disease