EEF2K (Human) Recombinant Protein
产品名称： EEF2K (Human) Recombinant Protein
英文名称： EEF2K (Human) Recombinant Protein
产品编号： P5544
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human EEF2K (NP_037434.1, 1 a.a. - 725 a.a.) full-length recombinant protein with GST tag expressed in Escherichia coli.
- Theoretical MW (kDa):
- 109
- Form:
- Liquid
- Preparation Method:
- Escherichia coli expression system
- Purification:
- Glutathione sepharose chromatography
- Purity:
- 81 % by SDS-PAGE/CBB staining
- Activity:
- The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorecence-labeled substrate, Mg(or Mn)/ATP, and Ca/Calmodulin . The phosphorylated and unphosphorylated substrates were separated and detected by LabChip 3000. Substrate: EEF2Ktide. ATP: 100 uM.
- Storage Buffer:
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 1 ug protein in SDS-PAGE
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 29904
- Protein Accession#:
- NP_037434.1
- Gene Name:
- EEF2K
- Gene Alias:
- HSU93850,MGC45041,eEF-2K
- Gene Description:
- eukaryotic elongation factor-2 kinase
- Omim ID:
- 606968
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq
- Other Designations:
- calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase,calmodulin-dependent protein kinase III,eEF-2 kinase,elongation factor-2 kinase
- Related Disease