proinsulin / INS monoclonal antibody, clone 1G4
产品名称: proinsulin / INS monoclonal antibody, clone 1G4
英文名称: proinsulin / INS monoclonal antibody, clone 1G4
产品编号: MAB0612
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native INS.
- Immunogen:
- Native purified human INS.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Immunohistochemistry (Frozen sections)
- ELISA
- Sandwich ELISA
- Entrez GeneID:
- 3630
- Gene Name:
- INS
- Gene Alias:
- ILPR,IRDN
- Gene Description:
- insulin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq
- Other Designations:
- OTTHUMP00000011161,OTTHUMP00000011162,OTTHUMP00000196038,proinsulin
- Related Disease
- Addison Disease
- Adenomatous Polyps
- Alzheimer Disease
- Alzheimer disease
- Amenorrhea
- Anorexia Nervosa
- Atherosclerosis
- Autoimmune Diseases
- Autoimmune polyglandular syndrome
- Bile Duct Neoplasms
- Birth Weight
- Body Weight
- Breast cancer
- Breast Neoplasms
- Bulimia
- Carcinoma
- Carcinoma, Hepatocellular
- Cardiovascular Diseases
- Celiac Disease