PROC (Human) Recombinant Protein (P01)
产品名称: PROC (Human) Recombinant Protein (P01)
英文名称: PROC (Human) Recombinant Protein (P01)
产品编号: H00005624-P01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human PROC full-length ORF ( NP_000303.1, 1 a.a. - 461 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MWQLTSLLLFVATWGISGTPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSWAP
- Theoretical MW (kDa):
- 78.5
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 5624
- GeneBank Accession#:
- NM_000312.2
- Protein Accession#:
- NP_000303.1
- Gene Name:
- PROC
- Gene Alias:
- PC,PROC1
- Gene Description:
- protein C (inactivator of coagulation factors Va and VIIIa)
- Omim ID:
- 176860
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The PROC gene encodes protein C (EC 3.4.21.69), a vitamin K-dependent plasma glycoprotein that is a key component of the anticoagulant system. Protein C is cleaved to its activated form, 'activated protein C' (APC) on endothelial cells by the thrombin-thrombomodulin complex (MIM 176930; MIM 188040) and then acts as a serine protease to degrade the activated forms of coagulation factors V (F5; MIM 612309) and VIII (F8; see MIM 306700). Protein S (PROS1; MIM 176880), also a vitamin K-dependent plasma protein, functions as a cofactor to activated protein C.[supplied by OMIM
- Other Designations:
- -
- Gene Pathway
- Related Disease
- Acute Disease
- Cadaver
- Cardiovascular Diseases
- Chorioamnionitis
- Coronary Artery Disease
- Coronary Disease
- Diabetes Mellitus, Type 2
- Edema
- Fetal Membranes, Premature Rupture
- Genetic Predisposition to Disease
- Inflammation
- Kidney Failure, Chronic
- Meningococcal Infections
- Multiple Organ Failure
- Obstetric Labor, Premature
- Postoperative Complications
- Pre-Eclampsia
- Pregnancy Complications, Hematologic
- Premature Birth